Glenza 40mg Tablet (Enzalutamide) Price, Uses & Side effects

GLENZA 40MG

Glenza is a hormonal therapy, for men who are all affected with prostate carcinoma in metastaic stage. Glenza 40mg Capsules are majorly indicated for prostate carcinoma, which contains Enzalutamide, as an active component considered as non steroidal anti-androgen medication.

PRODUCT DETAILS

Brand name : Glenza 

Active ingredient : Enzalutamide 

Strength :40MG 

COMPANY NAME : Glenmark

TAB COUNT : 28 tablets

Glenza 40mg

Mechanism of Action

An androgen which is a male hormone is used to develop prostate carcinoma. One of the major hormone secreted by testes and adrenal glands is known as testosterone. Glenza containing Enzalutamide will interfere with testosterone production, causes tumor cell growth depletion. Glenza interfere with androgen receptor signaling transduction and leads to cancer cell lysis.

DOSAGE

DOSING CONDITIONS AND ADMINISTRATION 

The usual prescribed dosage of Glenza is 160mg as a single dose by taking with or without food. Glenza is available in the strength of 40mg; four Capsuless of Glenza should be administered at a same time. Glenza Capsules should not crush, not chew taken with glass of water. Dose adjustment: In patients with ≥ grade III toxicity: Glenza 40mg therapy should be refuse for one week or the symptoms should be reduced to grade II, then restart with same dose or decreased to 80mg or 120mg Strong CYP2C8 inhibitors: While combining with Glenza Capsules, the dosage should be modified by reducing to 80mg as a single dose or avoid this combination. Strong CYP3A4 inducers: Co administration of Glenza with Strong CYP3A4 inducers, the dosage of Glenza Capsules increased up to 240mg or stop this combination.

SIDE EFFECTS

Some side effects during the therapy using with Glenza; Back pain, Arthralgia, Muscular weakness, pain, Diarrhea, Hypertension & hot flush, Dizziness, headache, Asthenia conditions, Peripheral edema, Spinal cord compression, paresthesia, Mental impairment, Hypesthesia, Respiratory tract infections, Hematuria, Pollakiuria, Dry skin, Pruritus, Neutropenia, Thrombocytopenia, Increasing bilirubin level, Epistaxis, Infections like sepsis, Fractures, joint injury, and hematomas (Fall associated injuries). Hallucinations.

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