Soranib 200mg tablet - Sorafenib Uses & Side effects

Soranib 200mg Tablet



Soranib belongs to a class of multi kinase inhibitors, the main ingredient which is used as sorafenib. 

It is not used as curable medicine but Soranib is used to reduce the growth rate of cancer cells by barrier the actions of an aberrant protein signal transduction helps to develop the cancer cells. Soranib is mechanism by depleting the blood supply to the cancer cells and stop their division and production.


PRODUCT DETAILS


Brand Name               Soranib 
Available Dose           200 mg
Composition               Sorafenib Tosylate
Manufactured by        Cipla Ltd 
Dosage Form              Tablets 
Packing                       Pack of 120 Tablets

Soranib 200mg Tablet
Soranib 200mg Tablet

DRUG INTERACTION


Soranib 200mg tablet interaction with carbamazepine + dexamethasone + Phenobarbital + phenytoin + rifamipicin leads to reduce in Sorafenib plasma concentration. Soranib interaction with doxorubicin and irinotecan will increase the plasma concentration.


SORAFENIB SIDE EFFECTS


Common Sorafenib Side Effects

Mouth dryness ; throat soreness ; Tiredness :Acne ; Dry skin ; Nausea ; Itching or rash skin ; Vomiting, ; Diarrhea ; Patchy hair thinning, ; decreased appetite ; Stomach pain ; etc.

Serious Side Effects

Chest heavy feeling ; Sudden weakness ; Increased blood pressure ; Bloody stools ; Coughing up blood / vomit ; fast heart rate ; low concentration ;; dermatology problem; jaundice etc.


MECHANISM OF ACTION


Sorafenib is an oral anti-cancer drugs, and also an inhibitor of various protein kinases, as such as VEGFR, PDGFR and Raf family kinases, because of usage in different kinases it is commonly known for multikinase enzyme inhibitor that decreases cell proliferation in vitro, researchers still made to improve sorafenib mechanism of action to behave as effective inhibitor.



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