Lapahope 250mg tablet: Lapatinib Uses & Side effects | Apple pharmaceuticals

LAPAHOPE 250MG



Lapahope 250 mg tablets are classified as anti-cancer agent, which is orally active drug used for treating breast cancer.
Herduo tablets are classified as;
1. Tyrosine kinase prohibitor
2. Stop the HER2/neu& epidermal growth factor receptor activity
3. Targeted therapy 
4. Signal transduction prohibitor.


PRODUCT DETAILS

Brand Name : Lapahope
Composition : Lapatinib
Strength availability : 250mg 
Manufactured by : Glenmark Pharma
Pack : 150 tablets


PHARMACOLOGY

Absorption:

Incomplete and insufficient absorption, the time to peak plasma concentration is 4 hours after intake of drug.

Distribution :

The drug bounds to human plasma protein like albumin & alpha glycoprotein relatively 99%.

Metabolism :

Lapahope is a substrate of P-gp& BCRP and go through intensive metabolism by using CYPP3A4 & CYP3A5 with minimum contribution of CYP2C19 & CYP2C8.

Excretion :

Elimination occurs via feces & urine.
Half-life time in 14.2 hours reaches by single dose of Herduo and multiple dosing reaches in 24 hours.


CONTRAINDICATION

The patients who are contraindicated to the component present in Lapahope tablet then Hypersentivity reaction occurs.



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