Sorafenat 200mg tablet - Sorafenib Uses & Side effects

Sorafenat 200mg Tablet



Sorafenat belongs to a class of multi kinase inhibitors, the main ingredient which is used as sorafenib.

It is not used as curable medicine but Sorafenat is used to reduce the growth rate of cancer cells by barrier the actions of an aberrant protein signal transduction helps to develop the cancer cells. Sorafenat is mechanism by depleting the blood supply to the cancer cells and stopa their division and production.

Sorafenat 200mg
Sorafenat 200mg


PRODUCT DETAILS


Brand Name                Sorafenat 
Available Dose            200 mg
Composition                Sorafenib Tosylate 
Manufactured by         Natco Pharma Ltd. 
Dosage Form               Tablets 
Packing                        Pack of 120 Tablets


DRUG INTERACTION


Sorafenat 200mg tablet interaction with carbamazepine + dexamethasone + Phenobarbital + phenytoin + rifamipicin leads to reduce in Sorafenib plasma concentration. Sorafenat interaction with doxorubicin and irinotecan will increase the plasma concentration.


SORAFENIB SIDE EFFECTS


Common Sorafenib Side Effects: mouth dryness ; throat soreness ; Tiredness :Acne ; Dry skin ; Nausea ; Itching or rash skin ; Vomiting, ; Diarrhea ; Patchy hair thinning, ; decreased appetite ; Stomach pain ; etc.
Serious Side Effects : Chest heavy feeling ; Sudden weakness ; Increased blood pressure ; Bloody stools ; Coughing up blood / vomit ; fast heart rate ; low concentration ;; dermatology problem; jaundice etc.

MECHANISM OF ACTION


Sorafenib is an oral anti-cancer drugs, and also an inhibitor of various protein kinases, as such as VEGFR, PDGFR and Raf family kinases, because of usage in different kinases it is commonly known for multikinase enzyme inhibitor that decreases cell proliferation in vitro, researchers still made to improve sorafenib mechanism of action to behave as effective inhibitor.



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